Applying to medical school is a significant milestone, but the application process itself can feel overwhelming—especially when you realize that not all schools use the same system. If you’re considering MD programs, DO programs, or Texas medical schools, you’ll need to apply through one (or more) of the three primary medical school application systems: AMCAS (American Medical College Application Service), AACOMAS (American Association of Colleges of Osteopathic Medicine Application Service), or TMDSAS (Texas Medical and Dental Schools Application Service).

At AcceptMed, we help medical school applicants navigate the complexities of each application system, ensuring they apply strategically to maximize their chances of acceptance. Understanding the key differences between AMCAS, AACOMAS, and TMDSAS will help you determine which system aligns best with your medical school goals.

Overview of AMCAS, AACOMAS, and TMDSAS

Each application system is designed for specific types of medical schools and has its own deadlines, structure, and unique requirements. Here’s a breakdown:

• AMCAS: Used for all MD (allopathic) programs in the U.S. except Texas schools.
• AACOMAS: Used for all DO (osteopathic) medical schools in the U.S.
• TMDSAS: Used exclusively for Texas MD, DO, and dental schools.

If you’re applying to a mix of MD and DO schools, you’ll need to submit applications through both AMCAS and AACOMAS. If you’re applying to Texas schools, you’ll most likely need to go through TMDSAS, as many Texas medical schools do not accept AMCAS applications.

Key Differences Between AMCAS, AACOMAS, and TMDSAS

Application Fees & Costs

• AMCAS: $175 for the first school + $45 for each additional school.
• AACOMAS: $198 for the first school + $55 for each additional school.
• TMDSAS: Flat fee of $200 for all Texas schools.

Takeaway: If you’re applying to multiple Texas schools, TMDSAS is the most cost-effective option. However, if you're applying to both MD and DO programs, costs can add up quickly across different application systems.

Personal Statement Length

• AMCAS: 5,300 characters.
• AACOMAS: 5,300 characters.
• TMDSAS: 5,000 characters.

Takeaway: If you’re applying through TMDSAS, you’ll need to trim your personal statement slightly to fit the 5,000-character limit.

Work & Activities Section

• AMCAS: Allows up to 15 activity entries, with three designated as “Most Meaningful.”
• AACOMAS: Unlimited activity entries, but no "Most Meaningful" designation.
• TMDSAS: Unlimited activity entries, but requires hours and supervisor contact information for each.

Takeaway: If you have extensive extracurriculars, AACOMAS and TMDSAS allow you to list more activities than AMCAS. However, AMCAS gives you a chance to highlight your three most impactful experiences, which can help focus your narrative.

Letters of Recommendation

• AMCAS: Committee letter or up to 10 individual letters.
• AACOMAS: Committee letter or up to 6 individual letters.
• TMDSAS: Only accepts three individual letters (or a committee letter).

Takeaway: TMDSAS applicants must be selective with their letters since only three are allowed (unless using a committee letter).

Which Application System Best Fits Your Medical School Goals?

Now that you understand the differences, let’s discuss which application system aligns with your goals.

If You’re Focused on MD Schools → Apply Through AMCAS

• The gold standard for MD applicants.
• Required for nearly every allopathic (MD) medical school in the U.S. except Texas.
• If you want to pursue a competitive specialty, MD programs tend to have more residency options.

If You Want to Apply to DO Schools → Apply Through AACOMAS

• The exclusive application service for osteopathic (DO) medical schools.
• No limit on activities you can list.
• A great option for students who resonate with holistic medicine and Osteopathic Manipulative Treatment (OMT).

If You’re Applying to Texas Medical Schools → Apply Through TMDSAS

• Used for both MD and DO schools in Texas (plus dental schools).
• Lower cost compared to AMCAS and AACOMAS.
• More favorable in-state tuition and Texas resident preference (out-of-state applicants face greater competition).

If You’re Applying to a Mix of MD, DO, and Texas Schools → Use Multiple Systems

• Many students apply through AMCAS and AACOMAS to maximize their options.
• If applying to Texas schools as well, expect to juggle three application platforms.

Strategic Tips for a Successful Application Cycle

• Apply early – AMCAS, AACOMAS, and TMDSAS operate on a rolling admissions basis, meaning submitting early increases your chances of acceptance.
• Double-check school requirements – Some Texas schools require TMDSAS, while others accept AMCAS or AACOMAS.
• Tailor your personal statement – Since each system has slightly different requirements, customizing your essay for each platform can make your application stronger.
• Choose your letters wisely – Especially for TMDSAS applicants, where only three individual letters are allowed.

Deciding between AMCAS, AACOMAS, and TMDSAS ultimately depends on your target schools, budget, and medical career goals.

• AMCAS is for MD programs (except Texas).
• AACOMAS is for DO programs.
• TMDSAS is required for most Texas medical schools.
• Each system has different requirements, fees, and deadlines—so plan accordingly.

By applying strategically, you can maximize your chances of getting into medical school while minimizing stress and unnecessary expenses.