AMCAS, AACOMAS, TMDSAS

AACOMAS vs. AMCAS: What DO Applicants Need to Know?

Medical School
July 8, 2025

Applying to medical school is already a complex process, but for students considering both MD (Doctor of Medicine) and DO (Doctor of Osteopathic Medicine) programs, the choice of application system adds another layer of decision-making. The two primary application services—AMCAS (for MD schools) and AACOMAS (for DO schools)—have distinct differences that DO applicants must understand before applying.

At AcceptMed, we help students navigate the nuances of these application systems, ensuring they maximize their chances of acceptance by making informed decisions. Whether you are exclusively applying to DO schools or considering both MD and DO programs, knowing the key differences between AACOMAS and AMCAS will help you streamline your application process and avoid unnecessary mistakes.

Understanding the Fundamental Differences Between AACOMAS and AMCAS

What is AMCAS?

  • The American Medical College Application Service (AMCAS) is the centralized application system used by all allopathic (MD) medical schools in the U.S. except for Texas, which has its own system (TMDSAS).
  • MD programs focus on traditional, evidence-based medicine and often place more emphasis on research and highly competitive specialties.

What is AACOMAS?

  • The American Association of Colleges of Osteopathic Medicine Application Service (AACOMAS) is used by students applying to osteopathic (DO) medical schools across the U.S.
  • DO programs emphasize a holistic approach to medicine, including Osteopathic Manipulative Treatment (OMT), which focuses on hands-on techniques to diagnose and treat patients.

Key Takeaway: AMCAS is for MD schools, while AACOMAS is for DO schools. If you are interested in both paths, you may need to apply through both systems.

Key Differences Between AACOMAS and AMCAS

Even though both application systems require similar components, there are notable differences in how applications are structured and reviewed.

Personal Statement

  • AMCAS and AACOMAS both require a 5,300-character personal statement, but the focus differs slightly.
  • MD programs expect applicants to highlight their scientific knowledge and evidence-based approach to medicine.
  • DO programs encourage applicants to showcase their understanding of osteopathic philosophy and holistic medicine.
  • Tip: If you are applying to both MD and DO schools, tailor your personal statement to each application or write a strong general statement that incorporates both approaches.

Work & Activities Section

  • AMCAS limits applicants to 15 entries for work, activities, and extracurriculars.
  • AACOMAS allows unlimited activity entries, giving students more flexibility to showcase their experiences.
  • Most Meaningful Experiences: AMCAS requires applicants to select three Most Meaningful experiences, while AACOMAS does not have this requirement.

Key Takeaway: If you have extensive clinical, volunteer, or leadership experiences, AACOMAS allows you to list more activities compared to AMCAS.

GPA Calculation Differences

  • AMCAS separates science GPA (BCPM – Biology, Chemistry, Physics, Math) from non-science GPA.
  • AACOMAS has a separate GPA calculation for “all science courses” and “all non-science courses.”
  • AACOMAS also allows for grade replacement (though not all schools consider this in admissions).

Key Takeaway: If you have retaken science courses to improve your GPA, AACOMAS may be more forgiving than AMCAS in some cases.

Rolling Admissions and Deadlines

  • Both AMCAS and AACOMAS operate on rolling admissions, meaning that applying early gives you the best chance of securing interviews and acceptance.
  • AACOMAS typically opens in early May, while AMCAS opens in late May or early June.
  • DO schools tend to review applications faster than MD schools, meaning you may receive interview invitations earlier in the cycle.

Key Takeaway: Regardless of which system you use, submitting your application early (May-June) is crucial for maximizing interview opportunities.

Should You Apply to Both MD and DO Schools?

Many students wonder whether they should apply to both MD and DO programs to increase their chances of acceptance. While it depends on your career goals, there are several factors to consider:

Reasons to Apply to Both MD and DO Schools

  • You want to maximize your chances of acceptance and are open to either training path.
  • You have a lower GPA or MCAT score and want to increase your options.
  • You are interested in holistic medicine but also want the option of traditional MD training.

Reasons to Apply Only to DO Schools

  • You strongly believe in the osteopathic philosophy and prefer a holistic, patient-centered approach.
  • You want to pursue primary care, family medicine, or other patient-focused specialties where DOs excel.
  • You prefer the DO curriculum, including OMT training, which is unique to osteopathic schools.

Key Takeaway: Applying to both MD and DO schools can be a smart strategy, but make sure your application is tailored to each path.

How to Strengthen Your AACOMAS Application as a DO Applicant

If you’re applying to DO schools through AACOMAS, there are a few strategies you can use to stand out in the admissions process.

Highlight Your Interest in Osteopathic Medicine

  • DO schools want to see that you understand and appreciate osteopathic philosophy.
  • Mention experiences that align with holistic, patient-centered care.
  • If you’ve shadowed a DO physician, include that in your Work & Activities section.

Gain Clinical Experience That Reflects a Holistic Approach

  • DO schools value hands-on patient interaction and a focus on preventative medicine.
  • Clinical experience in primary care, family medicine, or physical therapy can be particularly relevant.

Strongly Consider Shadowing a DO

  • Many DO schools prefer or require applicants to shadow a DO, so be proactive in setting up shadowing opportunities.
  • If you don’t have access to a DO, consider virtual shadowing programs or mention experiences that align with osteopathic principles.

Key Takeaway: DO schools are looking for applicants who genuinely align with osteopathic medicine—make sure your application reflects that.

Which Application System is Best for You?

Choosing between AMCAS and AACOMAS depends on your medical school goals, strengths, and career aspirations. If you’re considering both MD and DO programs, applying through both systems can maximize your chances of admission—but it’s essential to tailor your application to each path.

  • AMCAS is for MD schools; AACOMAS is for DO schools. If you want both, you may need to apply through both systems.
  • AACOMAS allows unlimited activities, while AMCAS limits entries to 15.
  • DO schools focus on holistic care, so demonstrating interest in osteopathic medicine is essential.
  • Applying early (May-June) in either system increases your chances of securing interviews and acceptances.
  • Tailor your personal statement and experiences to reflect the unique philosophies of MD and DO schools.

Applying to medical school is a long and competitive process, but by understanding the differences between AMCAS and AACOMAS, you can make strategic decisions that maximize your chances of success.

Keep Reading

More Relating Posts

The AcceptMed
Newsletter

Sign up to get regular admissions tips, advice, guides, and musings from our admissions experts delivered straight to your inbox. No spam, we promise.

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Got a question about us?
Send us a quick note

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.